Sublingual Immunotherapy: the Future of Allergy Treatment

Immunotherapy is the “tried and true” method of choice for medical treatment of allergies. Whereas pills like antihistamines can treat the symptoms of allergy, only immunotherapy has been shown to change the underlying allergic disease. It goes straight to the heart of the problem!


Immunotherapy starts with an allergy serum that contains traces of common allergens (pollens, pet dander, etc.) As the body is consistently exposed to these allergens, it can develop an immunity so it stops overreacting to them in ways that lead to bothersome allergy symptoms.

Immunotherapy can be given through allergy shots or through under-the-tongue (sublingual immunotherapy) drops. With shots, the allergy serum is injected into the skin and then absorbed into the blood stream. With sublingual immunotherapy drops, the serum is absorbed into the bloodstream through special cells in the mouth (known as mast cells).

Drops are widely used in Central Europe. In fact, around half of the people who receive allergy treatment there receive it through sublingual immunotherapy. Drops are quickly gaining traction in the U.S., too, not only because they are safer than shots but also because they are far easier to comply with. Because shots carry a greater risk of anaphylactic reaction than drops do, you have to take them at the doctor’s office. Most people take them twice a week. If you do the math, that’s a lot of time in the car.

Drops, however, can be taken at home or on the go. You simply take the prescribed squeeze bottle, dispense a few drops under your tongue, and continue with your standard activities.

Another big perk of sublingual immunotherapy is that it can be used for food allergies. (Shots can’t!)

Contact AllergyEasy to learn more about sublingual immunotherapy for food and pollen allergies.

About The Author

Stuart H. Agren, M.D.

Stuart H. Agren, M.D. completed his undergraduate studies at the University of Utah and went on to earn his Doctor of Medicine from Tulane University School of Medicine in 1974. He completed additional training at L.D.S. Hospital in Salt Lake City, Utah and then established his private medical practice starting in 1975. Dr. Agren completed a mini-residency in Industrial Medicine at the Robert Johnson School of Medicine at Rutgers University and also completed training to become a certified Medical Review Officer.

Dr. Agren was the Medical Director at TRW and McDonnell Douglas in Mesa, Arizona and at Stauffer Chemical and Kennecott Copper in Salt Lake City, Utah. He also served as an adjunct faculty member at Arizona State University.

In his private medical practice, Dr. Agren specialized in family practice and allergy. In his work as a private practice allergist, he was one of the first doctors in the country to prescribe sublingual immunotherapy to his patients as an alternative to subcutaneous immunotherapy (allergy shots). He has also been a trailblazer in the field of food allergy treatment and research, developing a program to treat multiple food allergies simultaneously using sublingual immunotherapy. Dr. Agren has been featured on local CBS, NBC, and ABC news affiliates and won the peer-nominated “Top Doc” award from Phoenix Magazine.

After 20 years in private practice, Dr. Agren became the Founder and President of AllergyEasy, which helps primary care physicians around the country offer allergy testing and sublingual immunotherapy treatment to their patients. Over 200 physicians in over 32 states use the AllergyEasy program to help their patients overcome environmental and food allergies and asthma.